Thiamine transporter 1, also known as thiamine carrier 1 (TC1) or solute carrier family 19 member 2 (SLC19A2) is a protein that in humans is encoded by the SLC19A2 gene. SLC19A2 is a thiamine transporter. Mutations in this gene cause thiamine-responsive megaloblastic anemia syndrome (TRMA), which is an … See more The SLC19A2 gene is located on the q arm of chromosome 1 in position 24.2 and spans 22,062 base pairs. The gene produces a 55.4 kDa protein composed of 497 amino acids. In the encoded protein (TC1), a See more The encoded protein is a high-affinity transporter specific to the intake of thiamine. Thiamine transport is not inhibited by other organic cations nor affected by See more This protein interacts with CERS2. See more • GeneReviews/NIH/NCBI/UW entry on Thiamine-Responsive Megaloblastic Anemia or Rogers Syndrome • SLC19A2+protein,+human at the U.S. National Library of … See more Mutations in the SLC19A2 gene can cause thiamine-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disease characterized by … See more • Scharfe C, Hauschild M, Klopstock T, Janssen AJ, Heidemann PH, Meitinger T, Jaksch M (September 2000). "A novel mutation in the thiamine responsive megaloblastic anaemia gene SLC19A2 in a patient with deficiency of respiratory chain complex I" See more WebImpaired Intestinal Vitamin B(1) (Thiamin) Uptake in Thiamin Transporter-2-Deficient Mice. Gastroenterology. 2010 May;138(5):1802-9. 18. Reidling JC, Rubin SA. Promoter Analysis of the Human Ascorbic Acid Transporters SVCT1 & 2: Mechanisms of Adaptive Regulation in Liver Epithelial Cells. J Nutr Biochem. 2011 Apr;22(4):344-50.
of all published cases of the early infantile SLC19A3 gene defect.
Web26 Nov 2024 · The brain needs thiamine (vitamin B1) as it helps the body’s cells to convert carbohydrates into energy, especially the brain’s nervous system. Vitamin B1, also called … WebVitamin B1 (auch: Thiamin) ist ein wasserlösliches Vitamin und besonders für den Energiestoffwechsel von Bedeutung – es wirkt als Coenzym bei der Energiegewinnung aus Kohlenhydraten. ... Aufgrund seiner Wirkung als Transporter für langkettige Fettsäuren wird L-Carnitin häufig zur Unterstützung des Fettstoffwechsels bei der ... make new ps4 account
Thiamine Transporter - an overview ScienceDirect Topics
Venlafaxine, a novel third‐generation antidepressant drug, has been described as a reference treatment for major depression, owing to its ability of inhibiting both noradrenalin and serotonin neuronal reuptake, and inhibiting dopamine reuptake slightly. However, its clinical application is hampered by a limited brain distribution. Glucosylation is an … Webammonium transporter plasma membrane AAH1 Adenine deaminase (adenine aminohydrolase), enzyme of the purine salvage pathway, has similarity to adenosine deaminases YNL141W adenine aminohydrolase (adenine deaminase) adenine catabolism adenine deaminase YIP3 COPII vesicle component YNL044W Interacts with YPT proteins Web27 Feb 2024 · In our first report, we used an in vitro transport–activity assay using purified ECF FolT2 reconstituted in proteoliposomes to identify hits 1 and 2 as inhibitors of the ECF FolT2 transporter . Specifically, we used the recombinant Escherichia coli MC1061 strain that cannot endogenously express ECF transporters but rather heterogeneously to … make new profile outlook